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About

About

I build machine-learning systems that pick out faint signals in noisy data. Most of the work is the engineering that makes them trustworthy: validating them with clinicians against clinical reference standards, and keeping them reliable once they are in clinical use.

Most of my work is on signals that are difficult to read. They are faint, they sit in a lot of noise, and they feed decisions where a wrong answer costs something.

I did a PhD in computational neuroscience at King’s College London, on deep learning and explainable AI for brain connectivity. Before and around that I spent more than eight years in industry, on the Linux kernel, embedded systems, and machine-learning platforms. I also co-founded a health-tech startup and looked after its technology. The common thread was getting a promising idea to work reliably once it left the notebook.

These days I work as a Research Software Engineer in the ECG Core Lab at the University of Glasgow, with Prof. Peter Macfarlane and Prof. Derek Connelly. The lab has developed the Glasgow ECG analysis program for more than fifty years, and it now helps read over 20 million recordings a year. My main project is a deep-learning layer that improves how the program detects atrial fibrillation. It reads the faint atrial part of the signal using weak-signal methods from astronomy and geophysics, and it strengthens the existing algorithm instead of replacing it. The code is used in clinics, so a mistake has real consequences, and we build it that way.

Day to day I work on detection in noise, time-series modelling, denoising, and anomaly detection. Astronomy and geophysics have spent decades refining the same methods to pull faint sources out of a loud background, and some of that thinking is already in the ECG work. I want to keep going in that direction, toward larger data and fainter signals.

01Toolbox

Toolbox

The languages, frameworks, and systems I reach for.

Languages

PythonJuliaRustC / C++R

ML / DL

PyTorchTensorFlowscikit-learnGraph Neural NetworksLLMs

Signal & data

Time-seriesSignal processingNumPy / SciPyPandasSpectral methods

Systems & scale

LinuxDockerHPC clustersGPU computingCI/CDGit

Domains

Clinical ECGNeuroimaging (fMRI / MRI)GenomicsMedical imaging

Always
learning

02Experience

Experience

Sixteen years across academia and industry, in research and engineering.

Apr 2025 — Present
academic

Research Software Engineer

University of Glasgow · Glasgow, UK

  • Working in the ECG Core Lab led by Prof. Peter Macfarlane and Prof. Derek Connelly, on the Glasgow ECG analysis program. The program is clinically deployed and helps interpret more than 20 million electrocardiograms a year.
  • Building a commercial deep-learning layer that improves atrial-fibrillation detection. It reads the faint atrial signal with methods borrowed from astronomy and geophysics.
  • Validating against expert-adjudicated reference standards and external databases, developing to IEC 60601-2-51 under an ISO 9001:2015 quality system.
  • Adding modern ML practice (rigorous evaluation, testing, reproducibility) to a codebase the lab has developed for over fifty years, so it stays dependable in clinical use.
Deep LearningAtrial FibrillationSignal ProcessingClinical MLPython
Jan 2023 — Nov 2025
industry

Co-founder & CTO

Tycho MedLink · London, UK

  • Co-founded a digital-therapeutics startup and led the technology for a VR treatment for Seasonal Affective Disorder, from prototype to clinical pilot.
  • Raised £100k across two UKRI rounds through the UCL and Cambridge alumni accelerators. Ran an early pilot with UCL Hospitals with promising results.
  • Built the VR product in Unity for Meta hardware, with instrumented user metrics.
Digital TherapeuticsVR / XRUnityClinical TrialsLeadership
Jan 2020 — Oct 2024
academic

PhD Researcher, Machine Learning & Neuroimaging

King's College London · London, UK

  • Developed graph neural networks with explainable-AI attribution (SmoothGrad, Grad-CAM) to predict neurodevelopmental outcomes from neonatal brain connectivity.
  • Worked in the CoDe Neuro lab alongside clinicians at the Centre for the Developing Brain. Results were published and presented at OHBM.
Deep LearningGraph Neural NetworksExplainable AIfMRI
Oct 2020 — Sep 2021
industry

Senior Research Engineer

Prepaire · Dubai, UAE (Remote)

  • Led development of AI models, including custom LLMs, that automated genomic data-analysis pipelines and cut processing time by around 40%.
  • Shipped the models into a high-performance production environment built to scale.
LLMsGenomicsPyTorchProduction ML
May 2022 — Jul 2022
teaching

Teaching Assistant, Deep Learning

Neuromatch · Remote

  • Taught deep learning with PyTorch and neuroimaging tooling to an international cohort. Ran daily labs and project work.
PyTorchTeachingNeuroimaging
Jul 2022 — Sep 2022
academic

Research Software Engineer

Google Summer of Code · London, UK

  • Built an infant eye-tracking API prototype, mentored by McGill University’s ophthalmology group.
PythonPyTorchMedical DevicesEye Tracking
Nov 2019 — Jan 2023
industry

Technical Editor, Computer Vision

RSIP Vision · Remote

  • Reviewed and summarised new computer-vision and medical-imaging research for Computer Vision News.
Computer VisionMedical ImagingTechnical Writing
Jan 2019 — Mar 2020
industry

Senior Machine Learning Engineer

Saddington Baynes · London, UK

  • Built AI image-processing automation in TensorFlow that cut manual work by about half. Set up GPU-accelerated Docker and CI/CD for model deployment.
TensorFlowGPU ComputingDockerCI/CD
Nov 2018 — Jan 2019
industry

Software Engineer, Linux Kernel

Microsoft · UK

  • Worked on cloud hypervisor performance and stability at the kernel level, in C. Contributed to virtualization R&D.
Linux KernelCVirtualizationSystems
Dec 2016 — Nov 2018
industry

Systems Software Engineer

Kano Computing · London, UK

  • Built and maintained a Linux-based OS, including system services and Qt/C++ and GTK applications. Cut the image build time from 4 hours to 30 minutes and added CI/CD.
LinuxC++QtDockerCI/CD
Mar 2014 — Jan 2016
academic

Research Software Engineer, Serious Games

University of Athens · Athens, Greece

  • Built an accessible “serious game” for children with mild disabilities (Epinoisi R&D), in PyGame and WebGL with a C++ game AI.
Game DevelopmentC++AccessibilityResearch
Jul 2009 — Dec 2013
industry

Embedded Systems Engineer

INTRACOM Defense Electronics · Athens, Greece

  • Embedded R&D (FPGA, microcontrollers) for a military communications system under NATO clearance. Built an automated test framework validated to NATO and MIL-STD requirements.
EmbeddedFPGACSignal Hardware
03Publications

Publications

Peer-reviewed papers, conference work, and abstracts.

2025

μ-Opioid Modulation of Sensorimotor Functional Connectivity in Autism: Insights from a Pharmacological Neuroimaging Investigation using Tianeptine

Dimitrov, M., Wong, N.M.L., Leaman, S., França, L.G.S., Valasakis, I., He, J., Lythgoe, D.J., Findon, J.L., Wichers, R.H., Stoencheva, V., Robertson, D.M., Blainey, S., Ivin, G., Holiga, Š., Tricklebank, M.D., Batalle, D., Murphy, D.G.M., McAlonan, G.M., Daly, E.

Biological Psychiatry Global Open Science

journalfMRIPharmacologyConnectivity
doi: 10.1016/j.bpsgos.2025.100663
2024

Explainable Deep Learning for Subtyping: A SmoothGrad Approach

Valasakis, I., Batalle, D., Deprez, M.

OHBM 2024

abstractXAISmoothGradSubtyping
2023

Predicting Neurodevelopmental Phenotypes from Neonatal Brain Connectivity using Graph Neural Networks

Valasakis, I., Batalle, D., Deprez, M., McAlonan, G.

OHBM 2023

abstractGraph Neural NetworksNeonatalBrain Connectivity
2021

Deep learning-based reconstruction for 3D coronary MR angiography with a 3D variational neural network (3D-VNN)

Qi, H., Hammernik, K., Lima da Cruz, G., Valasakis, I., Rueckert, D., Prieto, C., Botnar, R.

ISMRM 2021

conferenceDeep LearningMRIReconstruction3D-VNN
2019

Development of a Processing Toolset for Ion Mobility Mass Spectrometry

Valasakis, I.

MSc Thesis, Birkbeck, University of London

thesisSignal ProcessingMass SpectrometryData Processing
04Contact

Contact

Happy to talk about interesting problems in signals and machine learning. Email is the fastest way to reach me.

Open to

  • Research and engineering roles in signals and machine learning
  • Collaborations on time-series and detection problems
  • Speaking, peer review, and technical writing